Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | IL2 | P60568 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9330553 | 0.85 | ATM (0.45) | ATMKDM4EHTTLMNAMAPT | |
| SCHEMBL9330422 | 0.82 | ATM (0.48) | ATMKDM4EHTTLMNAMAPT | |
| SCHEMBL10839985 | 0.80 | KDM4E (0.42) | ATMKDM4EHTTLMNAMAPT | |
| SCHEMBL8818334 | 0.79 | ATM (0.49) | ATMKDM4EHTTLMNAMAPT | |
| SCHEMBL499545 | 0.79 | ATM (0.46) | ATMKDM4EHTTLMNAMAPT | |
| SCHEMBL11836656 | 0.79 | ATM (0.58) | ATMKDM4EHTTLMNAMAPT | |
| SCHEMBL9607486 | 0.79 | ATM (0.46) | ATMKDM4EHTTLMNAMAPT | |
| SCHEMBL9330931 | 0.79 | ATM (0.51) | ATMKDM4EHTTLMNAMAPT | |
| SCHEMBL10441956 | 0.78 | ATM (0.48) | ATMKDM4EHTTLMNAMAPT | |
| SCHEMBL8819228 | 0.77 | ATM (0.45) | ATMKDM4EHTTLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0816362-A1 | THIAZOLE DERIVATIVES | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1998-01-07 | — | — | EP | disclosed |