Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | IL2 | P60568 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9330422 | 0.84 | ATM (0.48) | ATMKDM4EHTTLMNAMAPT | |
| SCHEMBL8818334 | 0.82 | ATM (0.49) | ATMKDM4EHTTLMNAMAPT | |
| SCHEMBL499545 | 0.82 | ATM (0.46) | ATMKDM4EHTTLMNAMAPT | |
| SCHEMBL11836656 | 0.82 | ATM (0.58) | ATMKDM4EHTTLMNAMAPT | |
| SCHEMBL9330931 | 0.81 | ATM (0.51) | ATMKDM4EHTTLMNAMAPT | |
| SCHEMBL9607357 | 0.81 | KDM4E (0.41) | ATMKDM4EHTTLMNAMAPT | |
| SCHEMBL10441956 | 0.81 | ATM (0.48) | ATMKDM4EHTTLMNAMAPT | |
| SCHEMBL8819228 | 0.79 | ATM (0.45) | ATMKDM4EHTTLMNAMAPT | |
| SCHEMBL8553034 | 0.79 | ATM (0.45) | ATMKDM4EHTTLMNAMAPT | |
| SCHEMBL9607174 | 0.79 | KDM4E (0.42) | KDM4EMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069856-A1 | ANTIMALARIAL COMPOUNDS | LIVERPOOL SCHOOL OF TROPICAL MEDICINE (GB) | 2012-05-31 | — | — | WO | disclosed |