Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.44 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 4/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557780 | 0.91 | GPR119 (0.44) | GPR119CHEK2PRMT5FAAHDGAT2 | |
| SCHEMBL8556312 | 0.89 | PRMT5 (0.51) | GPR119PRMT5 | |
| SCHEMBL8553734 | 0.89 | GPR119 (0.42) | GPR119CHEK2PRMT5FAAHDGAT2 | |
| SCHEMBL8555211 | 0.88 | GPR119 (0.45) | GPR119CHEK2PRMT5FAAHDGAT2 | |
| SCHEMBL8555463 | 0.86 | GPR119 (0.40) | GPR119CHEK2PRMT5DGAT2 | |
| SCHEMBL8551336 | 0.86 | GPR119 (0.47) | GPR119CHEK2PRMT5FAAHDGAT2 | |
| Trifluoroacetic Acid SCHEMBL8552693 | 0.86 | CHEK2 (0.40) | GPR119CHEK2PRMT5DGAT2 | |
| Trifluoroacetic Acid SCHEMBL8552332 | 0.86 | PRMT5 (0.40) | GPR119CHEK2PRMT5DGAT2 | |
| Trifluoroacetic Acid SCHEMBL8555305 | 0.86 | PRMT5 (0.40) | GPR119CHEK2PRMT5DGAT2 | |
| SCHEMBL8552756 | 0.85 | GPR119 (0.45) | GPR119CHEK2PRMT5FAAHDGAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871442-A1 | BENZIMIDZOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1998-10-21 | — | — | EP | disclosed |
| WO-1997025041-A1 | BENZIMIDZOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1997-07-17 | — | — | WO | disclosed |