Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBLB | Q13191 | 16/20 | 0.56 |
| ▸ | CCKBR | P32239 | 2/20 | 0.46 |
| ▸ | CCKAR | P32238 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7552319 | 0.83 | CCKBR (0.52) | CCKBRCCKAR | |
| SCHEMBL7552311 | 0.83 | CCKBR (0.52) | CCKBRCCKAR | |
| SCHEMBL5800683 | 0.83 | CCKBR (0.52) | CCKBRCCKAR | |
| SCHEMBL6307970 | 0.81 | CCKBR (0.53) | CCKBRCCKAR | |
| SCHEMBL7552385 | 0.80 | CCKBR (0.49) | CCKBRCCKAR | |
| SCHEMBL7552389 | 0.80 | CCKBR (0.49) | CCKBRCCKAR | |
| SCHEMBL7552202 | 0.80 | CCKBR (0.47) | CCKBRCCKAR | |
| SCHEMBL7552197 | 0.80 | CCKBR (0.47) | CCKBRCCKAR | |
| SCHEMBL7549407 | 0.79 | CCKBR (0.48) | CCKBRCCKAR | |
| SCHEMBL7552285 | 0.79 | CCKBR (0.48) | CCKBRCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672037-B1 | 1,4-BENZODIAZEPINE DERIVATIVES AND THEIR USE AS CCK-MODULATORS | GLAXO GROUP LTD (GB) | 1998-07-08 | — | — | EP | disclosed |
| US-5569654-A | ADMINISTERING AS ANTAGONISTS OF GASTRIN AND CHOLECYSTOKININ | GLAXO GROUP LIMITED (GB) | 1996-10-29 | — | — | US | disclosed |