Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 12/20 | 0.44 |
| ▸ | MAOA | P21397 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | CALML3 | P27482 | 1/20 | 0.41 |
| ▸ | SDHA | P31040 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 6/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6966688 | 1.00 | MAOB (0.44) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL8173015 | 0.91 | MAOB (0.46) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL6967427 | 0.85 | CALML3 (0.51) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL6966680 | 0.84 | MAOB (0.49) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL7086427 | 0.84 | MAOB (0.49) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL6969860 | 0.80 | MAOA (0.66) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL6969868 | 0.80 | MAOA (0.66) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL1176669 | 0.76 | MAOB (0.50) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL6962239 | 0.74 | MAOB (0.51) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL8594959 | 0.74 | MAOB (0.51) | MAOBMAOALMNAPTGS1CALML3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882041-A1 | PIPERAZINONEPHENYLOXAZOLIDINONE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | AstraZeneca AB (SE) | 1998-12-09 | — | — | EP | disclosed |
| WO-1997027188-A1 | PIPERAZINONEPHENYLOXAZOLIDINONE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | ZENECA LIMITED (GB) | 1997-07-31 | — | — | WO | disclosed |