Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | PLA2G4B | P0C869 | 5/20 | 0.50 |
| ▸ | THRA | P10827 | 3/20 | 0.49 |
| ▸ | THRB | P10828 | 3/20 | 0.49 |
| ▸ | RARB | P10826 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4652888 | 0.81 | CXCR2 (0.51) | TP53TSHRPLA2G4BMEN1KMT2A | |
| SCHEMBL4651616 | 0.81 | CXCR2 (0.51) | TP53TSHRPLA2G4BMEN1KMT2A | |
| SCHEMBL4651710 | 0.81 | CXCR2 (0.51) | TP53TSHRPLA2G4BMEN1KMT2A | |
| SCHEMBL10537637 | 0.79 | PLA2G2A (0.56) | PLA2G2ATP53TSHRPLA2G4BTHRA | |
| SCHEMBL16429168 | 0.79 | PLA2G2A (0.56) | PLA2G2ATP53TSHRPLA2G4BTHRA | |
| SCHEMBL9580691 | 0.79 | TP53 (0.49) | PLA2G2ATP53TSHRPLA2G4BTHRA | |
| SCHEMBL8752104 | 0.76 | TSHR (0.57) | PLA2G2ATP53TSHRPLA2G4BTHRA | |
| SCHEMBL6858057 | 0.75 | PLA2G2A (0.51) | PLA2G2ATP53TSHRPLA2G4BTHRA | |
| SCHEMBL10536146 | 0.75 | PLA2G2A (0.51) | PLA2G2ATP53TSHRPLA2G4BTHRA | |
| SCHEMBL4651707 | 0.74 | TSHR (0.48) | PLA2G2ATP53TSHRPLA2G4BRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5859251-A | SYMMETRICAL CHROMOPHORES | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1999-01-12 | — | — | US | disclosed |