Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 10/20 | 0.49 |
| ▸ | GRIA2 | P42262 | 10/20 | 0.49 |
| ▸ | GRIA3 | P42263 | 10/20 | 0.49 |
| ▸ | GRIA4 | P48058 | 10/20 | 0.49 |
| ▸ | GRIN2D | O15399 | 8/20 | 0.49 |
| ▸ | GRIN3B | O60391 | 8/20 | 0.49 |
| ▸ | GRIN1 | Q05586 | 8/20 | 0.49 |
| ▸ | GRIN2A | Q12879 | 8/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 8/20 | 0.49 |
| ▸ | GRIN2C | Q14957 | 8/20 | 0.49 |
| ▸ | GRIN3A | Q8TCU5 | 8/20 | 0.49 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | LTK | P29376 | 1/20 | 0.39 |
| ▸ | GRK5 | P34947 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556101 | 0.88 | GRIN2D (0.39) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL8557905 | 0.88 | GRIN2D (0.43) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL8557253 | 0.86 | GRIN2D (0.47) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL8559120 | 0.86 | ADORA3 (0.50) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL8557884 | 0.85 | ADORA3 (0.49) | CHEK1DAPK3PRKD3METPDGFRA | |
| SCHEMBL8558860 | 0.82 | CHEK1 (0.36) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL8557394 | 0.81 | GRIA1 (0.55) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL8556134 | 0.81 | GRIA1 (0.42) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL8557815 | 0.81 | DAO (0.39) | CHEK1DAPK3PRKD3METPDGFRA | |
| SCHEMBL8557555 | 0.81 | PDE5A (0.45) | CHEK1DAPK3PRKD3METPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691970-B1 | IMIDAZOLOQUINOXALINONE DERIVATIVES AS EAA ANTAGONISTS | BASF AG (DE) | 1998-11-11 | — | — | EP | claimed |
| EP-0691970-B1 | IMIDAZOLOQUINOXALINONE DERIVATIVES AS EAA ANTAGONISTS | BASF AG (DE) | 1998-11-11 | — | — | EP | disclosed |