Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 5/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.59 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.50 |
| ▸ | SHBG | P04278 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TYR | P14679 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL39353 | 0.98 | CYP2C9 (0.61) | CYP2C9CYP2C19CYP1A2HSPA5SHBG | |
| SCHEMBL29357192 | 0.98 | CYP2C9 (0.61) | CYP2C9CYP2C19CYP1A2HSPA5SHBG | |
| SCHEMBL9413678 | 0.96 | CYP2C9 (0.59) | CYP2C9CYP2C19CYP1A2HSPA5SHBG | |
| SCHEMBL19730338 | 0.92 | CYP2C9 (0.55) | CYP2C9CYP2C19CYP1A2HSPA5SHBG | |
| SCHEMBL8772331 | 0.92 | ALDH1A1 (0.54) | CYP2C9CYP2C19CYP1A2HSPA5SHBG | |
| SCHEMBL14431974 | 0.91 | CYP2C9 (0.53) | CYP2C9CYP2C19CYP1A2HSPA5SHBG | |
| SCHEMBL5009340 | 0.88 | CYP2C9 (0.50) | CYP2C9CYP2C19CYP1A2HSPA5SHBG | |
| SCHEMBL526641 | 0.87 | ALDH1A1 (0.61) | CYP2C9CYP2C19CYP1A2HSPA5ALDH1A1 | |
| SCHEMBL2163415 | 0.87 | CYP2C19 (0.53) | CYP2C9CYP2C19CYP1A2HSPA5SHBG | |
| SCHEMBL26185875 | 0.86 | CYP2C9 (0.49) | CYP2C9CYP2C19CYP1A2HSPA5SHBG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE36128-E | STABILIZER FOR ORGANIC COMPOUNDS | ALBEMARLE CORPORATION (US) | 1999-03-02 | — | — | US | disclosed |
| EP-0280938-B1 | Antioxidant aromatic fluorophosphites | ETHYL CORP (US) | 1994-06-15 | — | — | EP | disclosed |
| US-4912155-A | Containing substituted aryl group | ETHYL CORPORATION (US) | 1990-03-27 | — | — | US | disclosed |
| EP-0280938-A1 | Antioxidant aromatic fluorophosphites | ALBEMARLE CORPORATION (US) | 1988-09-07 | — | — | EP | disclosed |