Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8670645 | 0.80 | CYP3A4 (0.48) | NR1I2CYP3A4CYP2D6TDP1L3MBTL1 | |
| SCHEMBL8555193 | 0.80 | NR1I2 (0.41) | NR1I2CYP3A4CYP2D6TDP1L3MBTL1 | |
| SCHEMBL9200266 | 0.80 | NR1I2 (0.73) | NR1I2CYP3A4CYP2D6TDP1L3MBTL1 | |
| SCHEMBL8912937 | 0.80 | NR1I2 (0.47) | NR1I2CYP3A4CYP2D6TDP1L3MBTL1 | |
| SCHEMBL9205929 | 0.80 | NR1I2 (0.57) | NR1I2CYP3A4CYP2D6TDP1L3MBTL1 | |
| SCHEMBL8666649 | 0.79 | CYP3A4 (0.46) | NR1I2CYP3A4CYP2D6TDP1L3MBTL1 | |
| SCHEMBL16086028 | 0.79 | CYP3A4 (0.46) | NR1I2CYP3A4CYP2D6TDP1L3MBTL1 | |
| SCHEMBL9087864 | 0.78 | NR1I2 (0.47) | NR1I2CYP3A4CYP2D6TDP1L3MBTL1 | |
| SCHEMBL8824422 | 0.78 | NR1I2 (0.53) | NR1I2CYP3A4CYP2D6TDP1L3MBTL1 | |
| SCHEMBL8552613 | 0.77 | NR1I2 (0.47) | NR1I2CYP3A4CYP2D6TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846986-A | Therapeutic phenoxyalkylazoles and phenoxyalkylazines | SANOFI (FR) | 1998-12-08 | — | — | US | disclosed |
| US-5721261-A | TREATING PICORNAVIRUS INFECTIONS | SANOFI PHARMACEUTICALS, INC. (US) | 1998-02-24 | — | — | US | disclosed |
| US-5552420-A | TREATING PICORNAVIRAL INFECTIONS | STERLING WINTHROP INC. (US) | 1996-09-03 | — | — | US | disclosed |