Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | B3GNT2 | Q9NY97 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 5/20 | 0.47 |
| ▸ | HTR2A | P28223 | 4/20 | 0.47 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5066699 | 0.88 | KDM4E (0.51) | B3GNT2KDM4EHTR2CHTR2APLA2G4A | |
| SCHEMBL30444101 | 0.84 | MCL1 (0.50) | B3GNT2MCL1KDM4EALDH1A1POLB | |
| SCHEMBL29343021 | 0.84 | KDM4E (0.69) | KDM4EALDH1A1POLBHPGDAPOBEC3A | |
| SCHEMBL28246496 | 0.84 | MCL1 (0.54) | MCL1KDM4EALDH1A1POLBHPGD | |
| SCHEMBL30622502 | 0.83 | MCL1 (0.53) | MCL1KDM4EALDH1A1POLBHPGD | |
| SCHEMBL5387046 | 0.83 | MCL1 (0.53) | MCL1KDM4EALDH1A1POLBHPGD | |
| SCHEMBL5981752 | 0.80 | MCL1 (0.57) | MCL1KDM4EALDH1A1POLBHPGD | |
| SCHEMBL3785550 | 0.80 | MCL1 (0.51) | MCL1KDM4EALDH1A1POLBHPGD | |
| SCHEMBL11974988 | 0.79 | KDM4E (0.48) | KDM4EALDH1A1POLBHPGDAPOBEC3A | |
| SCHEMBL1664172 | 0.78 | MCL1 (0.55) | MCL1KDM4EALDH1A1POLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151519-A2 | PPARG MODULATORS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATIN, INCORPORATED (US) | 2024-07-18 | — | — | WO | disclosed |
| EP-0820441-A1 | INDOLE DERIVATIVES AS cGMP-PDE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-01-28 | — | — | EP | disclosed |