Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.51 |
| ▸ | PLA2G4A | P47712 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15921713 | 0.88 | PLA2G4A (0.55) | PLA2G4AKDM4EKMT2APPARGPPARD | |
| SCHEMBL5387046 | 0.84 | MCL1 (0.53) | MCL1PLA2G4AKDM4EALDH1A1HPGD | |
| SCHEMBL30622502 | 0.84 | MCL1 (0.53) | MCL1PLA2G4AKDM4EALDH1A1HPGD | |
| SCHEMBL28246496 | 0.82 | MCL1 (0.54) | MCL1PLA2G4AKDM4EALDH1A1HPGD | |
| SCHEMBL5981752 | 0.81 | MCL1 (0.57) | MCL1PLA2G4AKDM4EALDH1A1HPGD | |
| SCHEMBL8553607 | 0.80 | B3GNT2 (0.50) | MCL1PLA2G4AKDM4EALDH1A1HPGD | |
| SCHEMBL1664172 | 0.79 | MCL1 (0.55) | MCL1PLA2G4AKDM4EALDH1A1HPGD | |
| SCHEMBL13139567 | 0.79 | NTSR1 (0.45) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL3351795 | 0.79 | MCL1 (0.61) | MCL1PLA2G4AKDM4EALDH1A1HPGD | |
| SCHEMBL30443986 | 0.79 | MCL1 (0.49) | MCL1PLA2G4AKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2206715-A1 | Fused heterotetracyclic compounds and use thereof as hcv polymerase inhibitor | Japan Tobacco, Inc. (JP) | 2010-07-14 | — | — | EP | disclosed |