Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 7/20 | 0.60 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TYMP | P19971 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13721415 | 0.81 | ATM (0.59) | ADORA2AHSD17B10KDM4EHPGDALDH1A1 | |
| SCHEMBL1786973 | 0.79 | NPSR1 (0.62) | ADORA1ADORA2AHSD17B10KDM4EHPGD | |
| SCHEMBL14911562 | 0.78 | ADORA1 (0.64) | ADORA1ADORA2AHSD17B10KDM4EALDH1A1 | |
| SCHEMBL23461929 | 0.73 | ADORA2A (0.53) | ADORA1ADORA2AHSD17B10KDM4EALDH1A1 | |
| SCHEMBL14633614 | 0.73 | ALDH1A1 (0.43) | ADORA1ADORA2AHSD17B10KDM4EHPGD | |
| SCHEMBL24793414 | 0.73 | ADORA2A (0.53) | ADORA1ADORA2AHSD17B10KDM4EALDH1A1 | |
| SCHEMBL20229834 | 0.71 | ADORA2A (0.55) | ADORA1ADORA2AKDM4ENPC1LMNA | |
| SCHEMBL580124 | 0.71 | NPSR1 (0.59) | ADORA1ADORA2AKDM4EHPGDALDH1A1 | |
| SCHEMBL14611730 | 0.71 | HSD17B10 (0.51) | ADORA2AHSD17B10KDM4EHPGDALDH1A1 | |
| SCHEMBL4839374 | 0.71 | ENPP1 (0.49) | HPGDALDH1A1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0534443-B1 | 3,6-Disubstituted pyridazine derivatives | MITSUBISHI CHEM CORP (JP) | 1998-12-30 | — | — | EP | disclosed |
| US-5462941-A | 1-(cyclohexylalkylamino)-4-(phenyl, thienyl, or furyl) phthalazines; anti-platelet agglutination agents for treatment or prevention of cerebro- or cardiovascular disorders | MITSUBISHI CHEMICAL CORPORATION (JP) | 1995-10-31 | — | — | US | disclosed |
| EP-0534443-A1 | 3,6-Disubstituted pyridazine derivatives | Mitsubishi Chemical Corporation (JP) | 1993-03-31 | — | — | EP | disclosed |