Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 6/20 | 0.56 |
| ▸ | MAOB | P27338 | 3/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.53 |
| ▸ | SDHA | P31040 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CALML3 | P27482 | 1/20 | 0.53 |
| ▸ | F10 | P00742 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8550806 | 0.88 | MAOA (0.56) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL8552152 | 0.87 | MAOA (0.59) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL8553737 | 0.82 | MAOA (0.59) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL8552787 | 0.81 | MAOA (0.58) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6400275 | 0.80 | MAOA (0.61) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL3328443 | 0.79 | MAOA (0.76) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL3328441 | 0.79 | MAOA (0.76) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6399539 | 0.78 | MAOA (0.59) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6399543 | 0.78 | MAOA (0.59) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6098943 | 0.77 | MAOA (0.65) | MAOAMAOBPTGS1SDHALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0856002-A1 | PHENYLOXAZOLIDINONES HAVING A C-C BOND TO 4-8 MEMBERED HETEROCYCLIC RINGS | PHARMACIA & UPJOHN COMPANY (US) | 1998-08-05 | — | — | EP | disclosed |
| WO-1997009328-A1 | PHENYLOXAZOLIDINONES HAVING A C-C BOND TO 4-8 MEMBERED HETEROCYCLIC RINGS | PHARMACIA & UPJOHN COMPANY (US) | 1997-03-13 | — | — | WO | disclosed |