Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3836599 | 0.92 | PTGS1 (0.32) | CYP2D6PTGS1PDE4ALMNASLC6A6 | |
| SCHEMBL5054581 | 0.89 | APP (0.34) | — | |
| SCHEMBL16561479 | 0.89 | CYP2D6 (0.31) | CYP2D6 | |
| SCHEMBL1078938 | 0.87 | PTGS1 (0.35) | CYP2D6PTGS1PDE4ALMNASLC6A6 | |
| SCHEMBL35763 | 0.87 | PTGS1 (0.35) | CYP2D6PTGS1PDE4ALMNASLC6A6 | |
| SCHEMBL23242898 | 0.85 | PTGS1 (0.33) | CYP2D6PTGS1PDE4ALMNASLC6A6 | |
| SCHEMBL29538945 | 0.85 | CYP2D6 (0.35) | CYP2D6PTGS1PDE4ALMNASLC6A6 | |
| Water SCHEMBL8593341 | 0.83 | PTGS1 (0.32) | CYP2D6PTGS1PDE4ALMNASLC6A6 | |
| SCHEMBL8744652 | 0.80 | APP (0.37) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| SCHEMBL11237901 | 0.78 | EPHX2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0879233-A1 | CHINOLINE AND BENZIMIDAZOLE DERIVATIVES AS BRADYKININ AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-11-25 | — | — | EP | disclosed |
| WO-1997028153-A1 | CHINOLINE AND BENZIMIDAZOLE DERIVATIVES AS BRADYKININ AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-08-07 | — | — | WO | disclosed |
| EP-0596074-A1 | IMPROVED WASH TECHNIQUE FOR IMMUNOASSAY | EASTMAN KODAK COMPANY (US) | 1994-05-11 | — | — | EP | disclosed |
| WO-1993022679-A1 | IMPROVED WASH TECHNIQUE FOR IMMUNOASSAY | EASTMAN KODAK COMPANY (US) | 1993-11-11 | — | — | WO | disclosed |