SCHEMBL8744652

SCHEMBL8744652

O=S(=O)(O)CCCNC(CCO)(CCO)CCO

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.37
PTGS1 P23219 1/20 0.30
PDE4A P27815 1/20 0.30
LMNA P02545 1/20 0.30
SLC6A6 P31641 1/20 0.30
CYP2C19 P33261 1/20 0.30
BLM P54132 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5054581 0.92 APP (0.34) APP
SCHEMBL3836599 0.88 PTGS1 (0.32) APPPTGS1PDE4ALMNASLC6A6
SCHEMBL97942 0.83 APP (0.39) APPPTGS1PDE4ALMNASLC6A6
SCHEMBL1078787 0.83 APP (0.39) APPPTGS1PDE4ALMNASLC6A6
SCHEMBL2818663 0.82 APP (0.38) APPPTGS1PDE4ALMNASLC6A6
SCHEMBL29515023 0.82 APP (0.38) APPPTGS1PDE4ALMNASLC6A6
Potassium SCHEMBL30106126 0.82 APP (0.38) APPPTGS1PDE4ALMNASLC6A6
Hydrochloric Acid SCHEMBL9571802 0.82 APP (0.38) APPPTGS1PDE4ALMNASLC6A6
SCHEMBL8553870 0.80 CYP2D6 (0.33) PTGS1PDE4ALMNASLC6A6CYP2C19
SCHEMBL161583 0.79 APP (0.39) APPPTGS1PDE4ALMNASLC6A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0556352-B1 CAPILLARY ZONE ELECTROPHORESIS USING DYNAMIC COATING BUFFERS BECKMAN INSTRUMENTS INC (US) 1997-01-15 EP claimed
CN-113286609-B Multimeric T cell modulating polypeptides and methods of use thereof 库尔生物制药有限公司 2025-01-21 CN disclosed
CN-118852456-A Multimeric T cell modulating polypeptides and methods of use thereof CUE生物制药股份有限公司 2024-10-29 CN disclosed
CN-116096405-A Multimeric T cell modulating polypeptides and methods of use thereof CUE生物制药股份有限公司 2023-05-09 CN disclosed