Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 3/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14275582 | 0.84 | HDAC6 (0.46) | CYP3A4TSHRTDP1MAPTAPEX1 | |
| SCHEMBL4325512 | 0.84 | HDAC6 (0.46) | CYP3A4TSHRTDP1MAPTAPEX1 | |
| SCHEMBL19471892 | 0.83 | HDAC1 (0.49) | CYP3A4TSHRMAPTSLC6A2SLC6A4 | |
| SCHEMBL14275595 | 0.83 | HDAC1 (0.49) | CYP3A4TSHRMAPTSLC6A2SLC6A4 | |
| SCHEMBL17784780 | 0.83 | HDAC1 (0.49) | CYP3A4TSHRMAPTSLC6A2SLC6A4 | |
| SCHEMBL8554615 | 0.79 | SLC6A2 (0.47) | MAPTSLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL18768607 | 0.76 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3CYP2D6KCNH2 | |
| SCHEMBL7927546 | 0.76 | MEN1 (0.50) | CYP3A4TSHRTDP1MAPTAPEX1 | |
| SCHEMBL5193387 | 0.76 | MEN1 (0.50) | CYP3A4TSHRTDP1MAPTAPEX1 | |
| SCHEMBL7933807 | 0.76 | MEN1 (0.50) | CYP3A4TSHRTDP1MAPTAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1203599-A | Substitued pyrrolidinone, thiazolidinone or oxazolidinone as herbicides | ZENECA LTD (GB) | 1998-12-30 | — | — | CN | disclosed |
| EP-0863894-A1 | SUBSTITUTED PYRROLIDINONE, THIAZOLIDINONE OR OXAZOLIDINONE AS HERBICIDES | ZENECA LIMITED (GB) | 1998-09-16 | — | — | EP | disclosed |
| US-5705456-A | AZETIDIN-2-ONES | ZENECA LIMITED (GB) | 1998-01-06 | — | — | US | disclosed |
| WO-1997020838-A1 | SUBSTITUTED PYRROLIDINONE, THIAZOLIDINONE OR OXAZOLIDINONE AS HERBICIDES | ZENECA LIMITED (GB) | 1997-06-12 | — | — | WO | disclosed |