Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.49 |
| ▸ | CDC25B | P30305 | 10/20 | 0.45 |
| ▸ | APAF1 | O14727 | 6/20 | 0.45 |
| ▸ | CASP3 | P42574 | 5/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 5/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 5/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 4/20 | 0.45 |
| ▸ | SAE1 | Q9UBE0 | 4/20 | 0.45 |
| ▸ | UBA2 | Q9UBT2 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | THRB | P10828 | 3/20 | 0.45 |
| ▸ | RECQL | P46063 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19290 | 0.79 | KDR (0.61) | KDM4EGAAALDH1A1HPGDNPC1 | |
| SCHEMBL509972 | 0.77 | KDM4E (0.57) | KDM4EGAAALDH1A1HPGDNPC1 | |
| SCHEMBL4674979 | 0.76 | KDR (0.57) | KDM4EGAAALDH1A1HPGDNPC1 | |
| SCHEMBL9754369 | 0.74 | NOTUM (0.48) | KDM4EGAAALDH1A1HPGDLOXL2 | |
| SCHEMBL30305373 | 0.73 | KDR (0.78) | KDM4EGAAALDH1A1HPGDNPC1 | |
| SCHEMBL29639160 | 0.73 | TNKS (0.63) | KDM4EGAAALDH1A1HPGDNPC1 | |
| SCHEMBL828493 | 0.73 | TNKS (0.63) | KDM4EGAAALDH1A1HPGDNPC1 | |
| SCHEMBL29817803 | 0.71 | KDM4E (0.51) | KDM4EGAAALDH1A1HPGDNPC1 | |
| SCHEMBL13316854 | 0.71 | KDM4E (0.59) | KDM4EGAAALDH1A1HPGDNPC1 | |
| SCHEMBL27031075 | 0.71 | KDM4E (0.51) | KDM4EGAAALDH1A1HPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869954-A1 | NOVEL HETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1998-10-14 | — | — | EP | disclosed |
| WO-1996031499-A1 | NOVEL HETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1996-10-10 | — | — | WO | disclosed |