Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 6/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | NMT2 | O60551 | 1/20 | 0.39 |
| ▸ | NMT1 | P30419 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557953 | 0.93 | BCHE (0.46) | BCHERAB9ANPC1SMN1; SMN2POLB | |
| SCHEMBL8557775 | 0.86 | RAB9A (0.42) | BCHERAB9ANPC1SMN1; SMN2POLB | |
| SCHEMBL8555194 | 0.81 | SMN1; SMN2 (0.47) | RAB9ANPC1SMN1; SMN2POLBTDP1 | |
| SCHEMBL8553989 | 0.81 | RAB9A (0.47) | RAB9ANPC1SMN1; SMN2POLBTDP1 | |
| Hydrochloric Acid SCHEMBL8551600 | 0.81 | BCHE (0.42) | BCHERAB9ANPC1SMN1; SMN2POLB | |
| SCHEMBL8551098 | 0.81 | RAB9A (0.45) | RAB9ANPC1SMN1; SMN2POLBTDP1 | |
| SCHEMBL8554128 | 0.80 | RAB9A (0.46) | RAB9ANPC1SMN1; SMN2POLBTDP1 | |
| SCHEMBL8551903 | 0.78 | NPY1R (0.54) | BCHEDRD2DRD4 | |
| SCHEMBL8557031 | 0.78 | RAB9A (0.46) | RAB9ANPC1SMN1; SMN2POLBTDP1 | |
| Hydrochloric Acid SCHEMBL8551974 | 0.78 | RAB9A (0.41) | BCHERAB9ANPC1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871442-A1 | BENZIMIDZOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1998-10-21 | — | — | EP | disclosed |
| WO-1997025041-A1 | BENZIMIDZOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1997-07-17 | — | — | WO | disclosed |