Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 8/20 | 0.74 |
| ▸ | CTSK | P43235 | 7/20 | 0.74 |
| ▸ | MMP9 | P14780 | 2/20 | 0.55 |
| ▸ | MMP8 | P22894 | 2/20 | 0.55 |
| ▸ | MMP2 | P08253 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.52 |
| ▸ | CTSL | P07711 | 3/20 | 0.51 |
| ▸ | CTSB | P07858 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MMP14 | P50281 | 1/20 | 0.48 |
| ▸ | TACR1 | P25103 | 1/20 | 0.47 |
| ▸ | MME | P08473 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | CPA1 | P15085 | 1/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17137921 | 0.89 | CTSS (0.77) | CTSSCTSKMMP9MMP8CYP3A4 | |
| SCHEMBL17137918 | 0.89 | CTSS (0.77) | CTSSCTSKMMP9MMP8CYP3A4 | |
| SCHEMBL613640 | 0.89 | CTSS (0.76) | CTSSCTSKCYP3A4CTSLMME | |
| SCHEMBL29401990 | 0.89 | CTSS (0.76) | CTSSCTSKCYP3A4CTSLMME | |
| SCHEMBL4600435 | 0.89 | CTSS (0.76) | CTSSCTSKCYP3A4CTSLMME | |
| SCHEMBL4122289 | 0.89 | CTSS (0.76) | CTSSCTSKCYP3A4CTSLMME | |
| SCHEMBL7860818 | 0.86 | CTSS (0.79) | CTSSCTSKCYP3A4CTSLCTSB | |
| SCHEMBL5556848 | 0.85 | CTSS (0.67) | CTSSCTSKMMP9MMP8CYP3A4 | |
| SCHEMBL5557360 | 0.84 | CTSS (0.66) | CTSSCTSKMMP9MMP8CYP3A4 | |
| SCHEMBL16459632 | 0.84 | CTSS (0.66) | CTSSCTSKMMP9MMP8CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0848957-A1 | Fas LIGAND SOLUBILIZATION INHIBITOR | KANEBO LTD. (JP) | 1998-06-24 | — | — | EP | disclosed |