Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 16/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ACP1 | P24666 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8554917 | 0.90 | NPY1R (0.44) | NPY1RRAB9A | |
| SCHEMBL8553133 | 0.87 | NPY1R (0.42) | NPY1RACP1 | |
| SCHEMBL8555787 | 0.87 | NPY1R (0.40) | NPY1RACP1 | |
| Trifluoroacetic Acid SCHEMBL8552860 | 0.86 | NPY1R (0.48) | NPY1R | |
| SCHEMBL8551439 | 0.83 | NPY1R (0.42) | NPY1RNPC1RAB9AACP1 | |
| SCHEMBL8554556 | 0.79 | NPY1R (0.51) | NPY1R | |
| SCHEMBL8551506 | 0.79 | NPY1R (0.43) | NPY1RACP1 | |
| SCHEMBL8554871 | 0.78 | NPY1R (0.50) | NPY1RNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8551284 | 0.78 | NPY1R (0.50) | NPY1RNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8553363 | 0.78 | NPY1R (0.48) | NPY1RACP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871442-A1 | BENZIMIDZOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1998-10-21 | — | — | EP | disclosed |
| WO-1997025041-A1 | BENZIMIDZOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1997-07-17 | — | — | WO | disclosed |