Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 10/20 | 0.41 |
| ▸ | CTSS | P25774 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8286493 | 0.94 | BTK (0.46) | CTSKCTSSKMT2ACA1CA2 | |
| SCHEMBL5848683 | 0.94 | CTSK (0.42) | CTSKCTSSKMT2ACA1CA2 | |
| SCHEMBL6477906 | 0.92 | CTSK (0.44) | CTSKCTSSKMT2ACA1CA2 | |
| SCHEMBL8279336 | 0.80 | BTK (0.41) | CTSKCTSSKMT2ACA1CA2 | |
| SCHEMBL8288558 | 0.80 | BTK (0.41) | CTSKCTSSKMT2ACA1CA2 | |
| SCHEMBL16885211 | 0.79 | CYP2D6 (0.43) | CTSKCTSSKMT2ACA1CA2 | |
| SCHEMBL1273387 | 0.78 | AAK1 (0.48) | CTSKCTSSKMT2ACA1CA2 | |
| SCHEMBL1349093 | 0.78 | AAK1 (0.48) | CTSKCTSSKMT2ACA1CA2 | |
| SCHEMBL1349095 | 0.78 | AAK1 (0.48) | CTSKCTSSKMT2ACA1CA2 | |
| SCHEMBL571434 | 0.78 | CA1 (0.43) | CTSKCTSSKMT2ACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0712854-B1 | Baccatin derivatives and processes for preparing the same | TANABE SEIYAKU CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5608073-A | TAXANE INTERMEDIATES | TANABE SEIYAKU CO., LTD. (JP) | 1997-03-04 | — | — | US | disclosed |
| US-5589502-A | ANTITUMOR | TANABE SEIYAKU CO., LTD. (JP) | 1996-12-31 | — | — | US | disclosed |
| EP-0712854-A1 | Baccatin derivatives and processes for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1996-05-22 | — | — | EP | disclosed |