Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.72 |
| ▸ | NTRK1 | P04629 | 6/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | KCNJ6 | P48051 | 2/20 | 0.58 |
| ▸ | KCNJ3 | P48549 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.53 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.53 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8551416 | 0.89 | ALDH1A1 (0.70) | POLBNTRK1KCNJ6KCNJ3TSHR | |
| SCHEMBL8553577 | 0.88 | NTRK1 (0.61) | POLBNTRK1KMT2AKCNJ6KCNJ3 | |
| SCHEMBL8553463 | 0.87 | NTRK1 (0.65) | POLBNTRK1KMT2AKCNJ6KCNJ3 | |
| SCHEMBL8550596 | 0.87 | NTRK1 (0.65) | POLBNTRK1KMT2AKCNJ6KCNJ3 | |
| SCHEMBL8553193 | 0.86 | NTRK1 (0.64) | POLBNTRK1KMT2AKCNJ6KCNJ3 | |
| SCHEMBL8555225 | 0.85 | NTRK1 (0.62) | POLBNTRK1KMT2AKCNJ6KCNJ3 | |
| SCHEMBL8553763 | 0.85 | NTRK1 (0.62) | POLBNTRK1KMT2AKCNJ6KCNJ3 | |
| SCHEMBL8555682 | 0.85 | NTRK1 (0.62) | POLBNTRK1KCNJ6KCNJ3TSHR | |
| SCHEMBL8552018 | 0.85 | NTRK1 (0.62) | POLBNTRK1KCNJ6KCNJ3TSHR | |
| SCHEMBL8556588 | 0.84 | NTRK1 (0.67) | NTRK1KMT2AKCNJ6KCNJ3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | claimed |
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |