Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.87 |
| ▸ | MAPT | P10636 | 2/20 | 0.87 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.87 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 4/20 | 0.54 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11996369 | 1.00 | RAB9A (0.87) | RAB9AMAPTSMN1; SMN2HPGDNPSR1 | |
| SCHEMBL1999435 | 0.98 | RAB9A (0.90) | RAB9AMAPTSMN1; SMN2HPGDNPSR1 | |
| SCHEMBL7299163 | 0.93 | RAB9A (1.00) | RAB9AMAPTSMN1; SMN2HPGDNPSR1 | |
| SCHEMBL10683824 | 0.91 | RAB9A (0.72) | RAB9AMAPTSMN1; SMN2HPGDNPSR1 | |
| SCHEMBL10682756 | 0.91 | RAB9A (0.72) | RAB9AMAPTSMN1; SMN2HPGDNPSR1 | |
| SCHEMBL10675533 | 0.91 | RAB9A (0.72) | RAB9AMAPTSMN1; SMN2HPGDNPSR1 | |
| SCHEMBL10680795 | 0.91 | RAB9A (0.72) | RAB9AMAPTSMN1; SMN2HPGDNPSR1 | |
| SCHEMBL10675006 | 0.91 | RAB9A (0.72) | RAB9AMAPTSMN1; SMN2HPGDNPSR1 | |
| SCHEMBL10683303 | 0.91 | RAB9A (0.72) | RAB9AMAPTSMN1; SMN2HPGDNPSR1 | |
| SCHEMBL10680450 | 0.91 | RAB9A (0.72) | RAB9AMAPTSMN1; SMN2HPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0840725-A1 | AZETIDINONE DERIVATIVES FOR THE TREATMENT OF ATHEROSCLEROSIS | SMITHKLINE BEECHAM PLC (GB) | 1998-05-13 | — | — | EP | disclosed |
| WO-1997002242-A1 | AZETIDINONE DERIVATIVES FOR THE TREATMENT OF ATHEROSCLEROSIS | SMITHKLINE BEECHAM PLC (GB) | 1997-01-23 | — | — | WO | disclosed |