Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL8554619

O=C(O)C(F)(F)F.O=C(O)CCc1ccc(C(=O)CNC(=O)CCC2CCNCC2)cc1

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 14/20 0.59
ITGA2B P08514 14/20 0.59
ITGA2 P17301 2/20 0.40
EPHX2 P34913 1/20 0.38
F2 P00734 1/20 0.37
TACR1 P25103 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL8554642 0.81 ITGB3 (0.90) ITGB3ITGA2BITGA2
Trifluoroacetic Acid SCHEMBL8556791 0.75 ITGB3 (0.80) ITGB3ITGA2BITGA2
Trifluoroacetic Acid SCHEMBL7734277 0.74 KMT2A (0.48) ITGB3ITGA2B
Trifluoroacetic Acid SCHEMBL8555606 0.74 ITGB3 (0.64) ITGB3ITGA2B
Trifluoroacetic Acid SCHEMBL7723271 0.74 KMT2A (0.60) ITGB3ITGA2B
Trifluoroacetic Acid SCHEMBL29890740 0.73 ITGB3 (0.49) ITGB3ITGA2BITGA2
Trifluoroacetic Acid SCHEMBL19994597 0.71 ITGB3 (0.50) ITGB3ITGA2BTACR1
Trifluoroacetic Acid SCHEMBL7732466 0.71 KMT2A (0.45) ITGB3ITGA2B
Trifluoroacetic Acid SCHEMBL8559818 0.71 ITGB3 (0.75) ITGB3ITGA2BF2
Trifluoroacetic Acid SCHEMBL7736001 0.70 NPC1 (0.50) ITGB3ITGA2BITGA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0641770-B1 NOVEL COMPOUND WITH PLATELET AGGREGATION INHIBITOR ACTIVITY MEIJI SEIKA CO (JP) 1998-05-13 EP disclosed
US-5594004-A CARDIOVASCULAR DISORDERS AND ANTICOAGULANTS MEIJI SEIKA KABUSHIKI KAISHA (JP) 1997-01-14 US disclosed
EP-0641770-A1 NOVEL COMPOUND WITH PLATELET AGGREGATION INHIBITOR ACTIVITY MEIJI SEIKA KABUSHIKI KAISHA (JP) 1995-03-08 EP disclosed