Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PLEC | Q15149 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8554791 | 0.65 | SIRT6 (0.42) | SIRT6ADRB1KAT2BMAPTPOLB | |
| SCHEMBL11320631 | 0.65 | CYP1A2 (0.67) | MAPTPOLBMEN1KMT2ANPC1 | |
| SCHEMBL29242 | 0.65 | CYP1A2 (0.67) | MAPTPOLBMEN1KMT2ANPC1 | |
| SCHEMBL28180410 | 0.65 | CYP1A2 (0.67) | MAPTPOLBMEN1KMT2ANPC1 | |
| SCHEMBL2724772 | 0.65 | CYP1A2 (0.67) | MAPTPOLBMEN1KMT2ANPC1 | |
| Fluoride SCHEMBL8146479 | 0.63 | CYP1A2 (0.64) | MAPTPOLBMEN1KMT2ANPC1 | |
| SCHEMBL10506583 | 0.63 | CYP1A2 (0.64) | MAPTPOLBMEN1KMT2ANPC1 | |
| SCHEMBL28546705 | 0.63 | CYP1A2 (0.64) | MAPTPOLBMEN1KMT2ANPC1 | |
| SCHEMBL10506577 | 0.63 | CYP1A2 (0.64) | MAPTPOLBMEN1KMT2ANPC1 | |
| Hydrochloric Acid SCHEMBL28429390 | 0.63 | CYP1A2 (0.64) | MAPTPOLBMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0756598-B1 | SUBSTITUTED 5,6-DIHYDRO-5-OXO-1,4-DITHIINO-(2,3-D)-PYRIDAZINE-2,3-DICARBONITRILES, COMPOSITIONS CONTAINING THEM AND THEIR USE AS ANTIMICROBIALS | DOW CHEMICAL CO (US) | 1998-09-16 | — | — | EP | disclosed |
| EP-0756598-A1 | SUBSTITUTED 5,6-DIHYDRO-5-OXO-1,4-DITHIINO-(2,3-D)-PYRIDAZINE-2,3-DICARBONITRILES, COMPOSITIONS CONTAINING THEM AND THEIR USE AS ANTIMICROBIALS | THE DOW CHEMICAL COMPANY (a Delaware corporation) (US) | 1997-02-05 | — | — | EP | disclosed |
| US-5488051-A | BACTERICIDES, FUNGICIDES, ALGICIDES AND ANTIPROTOZOA AGENTS | THE DOW CHEMICAL COMPANY (US) | 1996-01-30 | — | — | US | disclosed |
| WO-1995029181-A1 | SUBSTITUTED 5,6-DIHYDRO-5-OXO-1,4-DITHIINO-(2,3-D)-PYRIDAZINE-2,3-DICARBONITRILES, COMPOSITIONS CONTAINING THEM AND THEIR USE AS ANTIMICROBIALS | THE DOW CHEMICAL COMPANY (US) | 1995-11-02 | — | — | WO | disclosed |