Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.57 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | NPY1R | P25929 | 1/20 | 0.56 |
| ▸ | NPY2R | P49146 | 1/20 | 0.56 |
| ▸ | BCHE | P06276 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556952 | 0.94 | MEN1 (0.60) | HSD17B10ABCB1ABCG2KDM4ELMNA | |
| SCHEMBL7208378 | 0.90 | SLC2A1 (0.52) | MAPK1HSD17B10KDM4ELMNAHTT | |
| SCHEMBL8554822 | 0.85 | MAPK1 (0.64) | MAPK1HSD17B10ABCB1ABCG2KDM4E | |
| SCHEMBL6672350 | 0.84 | TTR (0.60) | MAPK1HSD17B10ABCB1ABCG2KDM4E | |
| SCHEMBL31361425 | 0.84 | BCHE (0.60) | MAPK1HSD17B10ABCB1ABCG2KDM4E | |
| SCHEMBL2060386 | 0.84 | MAPK1 (0.63) | MAPK1HSD17B10ABCB1ABCG2KDM4E | |
| SCHEMBL3239903 | 0.84 | BCHE (0.60) | MAPK1HSD17B10ABCB1ABCG2KDM4E | |
| SCHEMBL3722770 | 0.84 | MAPK1 (0.59) | MAPK1HSD17B10ABCB1ABCG2KDM4E | |
| SCHEMBL10731044 | 0.83 | ALDH1A1 (0.69) | MAPK1HSD17B10ABCB1ABCG2KDM4E | |
| Phosphine SCHEMBL4434544 | 0.83 | TTR (0.59) | MAPK1HSD17B10ABCB1ABCG2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0617022-B1 | 6,7, dialkoxy-3,4-dihydroisoquinolin-8-ol, process for preparation thereof and process for preparation of 6,7-dialkoxy-1,2,3,4-tetrahydroisoquinolin-8-ol using the compound | BANYU PHARMA CO LTD (JP) | 1998-02-11 | — | — | EP | disclosed |
| US-5498717-A | CHEMICAL INTERMEDIATES FOR PRODUCING ANTITUMOR POTENTIATORS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-03-12 | — | — | US | disclosed |
| US-5446164-A | Regioselective cyclization of phenethylamide derivative in presence of phosphoric acid halide, reducing formed compound | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-08-29 | — | — | US | disclosed |