Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.68 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.68 |
| ▸ | TUBB | P07437 | 4/20 | 0.68 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.68 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.68 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.68 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.68 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.68 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.68 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.68 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.68 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.68 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.68 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.68 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.68 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.68 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.68 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14295074 | 1.00 | NPC1 (0.68) | NPC1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL12168451 | 1.00 | NPC1 (0.68) | NPC1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL8554576 | 0.98 | NPC1 (0.65) | NPC1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL16579871 | 0.98 | NPC1 (0.66) | NPC1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL9050854 | 0.96 | NPC1 (0.67) | NPC1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL9061162 | 0.95 | NPC1 (0.68) | NPC1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL16263256 | 0.95 | NPC1 (0.60) | NPC1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL8555520 | 0.94 | NPC1 (0.65) | NPC1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL12667934 | 0.93 | NPC1 (0.76) | NPC1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL8552119 | 0.92 | TUBB4A (0.64) | NPC1TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0712854-B1 | Baccatin derivatives and processes for preparing the same | TANABE SEIYAKU CO (JP) | 1998-07-01 | — | — | EP | claimed |
| US-5589502-A | ANTITUMOR | TANABE SEIYAKU CO., LTD. (JP) | 1996-12-31 | — | — | US | claimed |