Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7901695 | 0.65 | TSHR (0.32) | — | |
| SCHEMBL14687576 | 0.62 | TSHR (0.34) | TDP2MAPTSMAD3HSD17B10KDM4C | |
| SCHEMBL8552421 | 0.59 | — | — | |
| SCHEMBL8554416 | 0.58 | — | — | |
| SCHEMBL7554333 | 0.56 | — | — | |
| SCHEMBL13759658 | 0.55 | GLA (0.31) | — | |
| SCHEMBL14749975 | 0.53 | — | — | |
| SCHEMBL13736883 | 0.52 | — | — | |
| SCHEMBL14564226 | 0.51 | — | — | |
| SCHEMBL18306090 | 0.51 | TSHR (0.32) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0719265-B1 | NUCLEOSIDE DERIVATIVES, METHODS FOR THE MANUFACTURE THEREOF AND SPECIFIC POLYCLONAL AND MONOCLONAL ANTIBODIES OF SAID DERIVATIVES | COMMISSARIAT ENERGIE ATOMIQUE (FR) | 1998-12-02 | — | — | EP | claimed |
| US-5721341-A | Derivatives of nucleosides, processes for the production of these derivatives of nucleosides and specific polyclonal and monoclonal antibodies of these derivatives | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 1998-02-24 | — | — | US | claimed |