SCHEMBL7901695

SCHEMBL7901695

CC1C(=O)NC(=O)C1(C)O

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1567354 0.74 TSHR (0.35) TSHR
SCHEMBL6352307 0.70 TSHR (0.32) TSHR
SCHEMBL8554929 0.65 TDP2 (0.30)
SCHEMBL7834244 0.63 TSHR (0.41) TSHR
SCHEMBL14749975 0.62
SCHEMBL14687576 0.62 TSHR (0.34) TSHR
SCHEMBL48043 0.62 TSHR (0.34) TSHR
SCHEMBL11579920 0.60
SCHEMBL16024180 0.60 TSHR (0.31) TSHR
SCHEMBL3138269 0.59 TP53 (0.35) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6197409-B1 Ink-jet media E. I. DU PONT DE NEMOURS AND COMPANY 2001-03-06 US claimed