SCHEMBL8555074

SCHEMBL8555074

CCCC(C(=O)N1C(=O)OCC1Cc1ccccc1)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 3/20 0.47
IDH1 O75874 6/20 0.42
AGTR2 P50052 2/20 0.41
IL6ST P40189 1/20 0.41
CHRM1 P11229 5/20 0.40
NAAA Q02083 1/20 0.40
FAAH O00519 1/20 0.38
PPARG P37231 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8555423 0.91 GAA (0.46) PPARAIDH1AGTR2IL6STCHRM1
SCHEMBL7412086 0.87 PPARA (0.44) PPARAIDH1AGTR2IL6STNAAA
SCHEMBL9947401 0.87 CHRM1 (0.48) PPARAIDH1CHRM1
SCHEMBL29516311 0.87 PPARA (0.43) PPARAIDH1AGTR2IL6STNAAA
SCHEMBL1915787 0.86 PPARA (0.42) PPARAIDH1AGTR2IL6STCHRM1
SCHEMBL4448170 0.86 PPARA (0.54) PPARAIDH1AGTR2IL6STNAAA
SCHEMBL3689311 0.86 PPARA (0.54) PPARAIDH1AGTR2IL6STNAAA
SCHEMBL13625847 0.86 PPARA (0.54) PPARAIDH1AGTR2IL6STNAAA
SCHEMBL1915789 0.86 PPARA (0.42) PPARAIDH1AGTR2IL6STCHRM1
SCHEMBL9258788 0.84 PPARA (0.44) PPARAIDH1IL6STNAAAFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0848957-A1 Fas LIGAND SOLUBILIZATION INHIBITOR KANEBO LTD. (JP) 1998-06-24 EP disclosed