Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | BRD2 | P25440 | 1/20 | 0.44 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ACLY | P53396 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7358488 | 0.83 | KMT2A (0.56) | KMT2AMEN1MAPK1ALDH1A1LMNA | |
| SCHEMBL7361784 | 0.74 | PDE4D (0.61) | KMT2AMEN1MAPK1ALDH1A1LMNA | |
| SCHEMBL7358896 | 0.74 | KMT2A (0.70) | KMT2AMEN1MAPK1ALDH1A1LMNA | |
| SCHEMBL21947446 | 0.71 | MAPT (0.52) | KMT2AMAPK1ALDH1A1LMNA | |
| SCHEMBL21569521 | 0.71 | MAPT (0.52) | KMT2AMAPK1ALDH1A1LMNA | |
| SCHEMBL27997507 | 0.69 | HTR2C (0.56) | KMT2AMEN1 | |
| SCHEMBL15856028 | 0.69 | HTR6 (0.47) | KMT2AMEN1ALDH1A1HTTKEAP1 | |
| SCHEMBL27535581 | 0.68 | LRRK2 (0.47) | KMT2AMEN1ALDH1A1GAA | |
| SCHEMBL7359855 | 0.68 | KMT2A (0.64) | KMT2AMEN1MAPK1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL2719412 | 0.68 | HTR6 (0.46) | KMT2AMEN1ALDH1A1HTTKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0741707-B1 | SUBSTITUTED AROMATIC COMPOUNDS AS c.AMP PHOSPHODIESTERASE- AND TNF-INHIBITORS | RHONE POULENC RORER LTD (GB) | 1998-04-01 | — | — | EP | claimed |