Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.43 |
| ▸ | CASP3 | P42574 | 5/20 | 0.39 |
| ▸ | CASP2 | P42575 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 2/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | FER | P16591 | 1/20 | 0.34 |
| ▸ | LTK | P29376 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phthalimide SCHEMBL8558696 | 1.00 | GSK3B (0.43) | GSK3BCASP3CASP2CASP7CASP6 | |
| Phthalimide SCHEMBL8557340 | 1.00 | GSK3B (0.43) | GSK3BCASP3CASP2CASP7CASP6 | |
| Phthalimide SCHEMBL8559292 | 1.00 | GSK3B (0.43) | GSK3BCASP3CASP2CASP7CASP6 | |
| Phthalimide SCHEMBL8559114 | 1.00 | GSK3B (0.43) | GSK3BCASP3CASP2CASP7CASP6 | |
| Phthalimide SCHEMBL8559536 | 0.99 | GSK3B (0.44) | GSK3BCASP3CASP2CASP7CASP6 | |
| SCHEMBL8938070 | 0.96 | GSK3B (0.38) | GSK3BCASP3CASP2CASP7CASP6 | |
| SCHEMBL9151570 | 0.96 | GSK3B (0.38) | GSK3BCASP3CASP2CASP7CASP6 | |
| SCHEMBL4909203 | 0.96 | GSK3B (0.38) | GSK3BCASP3CASP2CASP7CASP6 | |
| SCHEMBL133934 | 0.96 | GSK3B (0.38) | GSK3BCASP3CASP2CASP7CASP6 | |
| SCHEMBL4026807 | 0.96 | GSK3B (0.38) | GSK3BCASP3CASP2CASP7CASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0575954-B1 | Aminoalkylcarbamic esters of eseroline suitable for use as cholinesterase acitivity inhibitors and relative preparation process | MEDIOLANUM FARMACEUTICI SRL (IT) | 1998-09-02 | — | — | EP | disclosed |