Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556303 | 0.83 | RAB9A (0.38) | RAB9AMEN1KMT2AKDRLMNA | |
| SCHEMBL1140961 | 0.81 | MAPT (0.39) | RAB9ASMN1; SMN2MEN1MAPTMAPK1 | |
| SCHEMBL8554676 | 0.81 | RAB9A (0.40) | RAB9AMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL1140910 | 0.81 | MAPT (0.39) | RAB9ASMN1; SMN2MEN1MAPTMAPK1 | |
| SCHEMBL8554096 | 0.81 | HRH3 (0.39) | RAB9AHRH3ALDH1A1ADRA2BADRA2C | |
| SCHEMBL1895510 | 0.81 | CHRM2 (0.41) | RAB9ASMN1; SMN2MEN1MAPTMAPK1 | |
| SCHEMBL1141072 | 0.80 | MAPT (0.38) | RAB9ASMN1; SMN2MEN1MAPTMAPK1 | |
| SCHEMBL1140923 | 0.80 | MEN1 (0.38) | RAB9ASMN1; SMN2MEN1MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL8558959 | 0.80 | HRH3 (0.38) | RAB9AHRH3ALDH1A1KCNH2 | |
| SCHEMBL8554050 | 0.78 | RAB9A (0.42) | RAB9ASMN1; SMN2MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543307-B1 | Nootropic agent | SANWA KAGAKU KENKYUSHO CO (JP) | 1998-05-06 | — | — | EP | claimed |
| US-5434165-A | Nootropic agents, compositions of, and method of use thereof | SANAWA KAGAKU KENKYUSHO COMPANY, LTD. (JP) | 1995-07-18 | — | — | US | claimed |
| JP-6184152-A | — | — | None | — | — | JP | disclosed |
| EP-0543307-B1 | Nootropic agent | SANWA KAGAKU KENKYUSHO CO (JP) | 1998-05-06 | — | — | EP | disclosed |
| US-5434165-A | Nootropic agents, compositions of, and method of use thereof | SANAWA KAGAKU KENKYUSHO COMPANY, LTD. (JP) | 1995-07-18 | — | — | US | disclosed |
| JP-H06184152-A | NEW COMPOUND, ITS PRODUCTION AND BRAIN FUNCTION IMPROVER USING THE SAME AS MAIN INGREDIENT | SANWA KAGAKU KENKYUSHO CO LTD | 1994-07-05 | — | — | JP | disclosed |
| EP-0543307-A2 | Nootropic agent | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1993-05-26 | — | — | EP | disclosed |