Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 13/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | NOTCH1 | P46531 | 2/20 | 0.35 |
| ▸ | NOTCH3 | Q9UM47 | 1/20 | 0.35 |
| ▸ | CCKAR | P32238 | 4/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | RBPJ | Q06330 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2927644 | 0.60 | CCKBR (0.78) | CCKBRCCKAR | |
| SCHEMBL7207460 | 0.60 | CCKBR (0.78) | CCKBRCCKAR | |
| SCHEMBL9272046 | 0.56 | CYP11B1 (0.54) | CCKBRKCNH2 | |
| SCHEMBL5706512 | 0.56 | KMT2A (0.44) | — | |
| SCHEMBL7746365 | 0.56 | MAPT (0.39) | — | |
| SCHEMBL11602590 | 0.54 | MAPT (0.65) | KCNH2 | |
| Atrolactamide SCHEMBL78236 | 0.54 | MAPT (0.65) | KCNH2 | |
| Ethane SCHEMBL3002447 | 0.54 | MAPT (0.59) | KCNH2 | |
| SCHEMBL6266546 | 0.54 | CYP2B6 (0.56) | — | |
| SCHEMBL14477084 | 0.54 | CA12 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672037-B1 | 1,4-BENZODIAZEPINE DERIVATIVES AND THEIR USE AS CCK-MODULATORS | GLAXO GROUP LTD (GB) | 1998-07-08 | — | — | EP | disclosed |