Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 2/20 | 0.46 |
| ▸ | CDC25A | P30304 | 1/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.43 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14134758 | 1.00 | KMT2A (0.50) | KMT2ACYP1A2CYP2D6CES1CDC25A | |
| SCHEMBL9868831 | 1.00 | KMT2A (0.50) | KMT2ACYP1A2CYP2D6CES1CDC25A | |
| SCHEMBL8708894 | 1.00 | KMT2A (0.50) | KMT2ACYP1A2CYP2D6CES1CDC25A | |
| SCHEMBL9736812 | 1.00 | KMT2A (0.50) | KMT2ACYP1A2CYP2D6CES1CDC25A | |
| SCHEMBL8475420 | 1.00 | KMT2A (0.50) | KMT2ACYP1A2CYP2D6CES1CDC25A | |
| SCHEMBL19746373 | 1.00 | KMT2A (0.50) | KMT2ACYP1A2CYP2D6CES1CDC25A | |
| SCHEMBL10448669 | 0.98 | KMT2A (0.51) | KMT2ACYP1A2CYP2D6CES1CDC25A | |
| SCHEMBL6093583 | 0.94 | KMT2A (0.53) | KMT2ACYP1A2CYP2D6CES1CDC25A | |
| SCHEMBL30996203 | 0.94 | CYP1A2 (0.55) | KMT2ACYP1A2CYP2D6CES1CDC25A | |
| SCHEMBL30996195 | 0.88 | KMT2A (0.40) | KMT2ACYP1A2CYP2D6CES1CDC25A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0529100-B1 | INDOLINOSPIROBENZOPYRAN DERIVATIVE | OTSUKA KAGAKU KK (JP) | 1998-11-11 | — | — | EP | disclosed |
| EP-0530369-B1 | CRYSTAL COMPRISING INDOLINOSPIROBENZOTHIOPYRAN DERIVATIVE AND RING-OPENING ISOMER THEREOF | OTSUKA KAGAKU KK (JP) | 1997-02-05 | — | — | EP | disclosed |
| US-5403702-A | Crystals consisting of an indolinospirobenzopyran derivative | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1995-04-04 | — | — | US | disclosed |
| US-5320784-A | Crystal comprising an indolinospirobenzothiopyran derivative and its ring opened isomer | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1994-06-14 | — | — | US | disclosed |
| EP-0530369-A1 | CRYSTAL COMPRISING INDOLINOSPIROBENZOTHIOPYRAN DERIVATIVE AND RING-OPENING ISOMER THEREOF | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1993-03-10 | — | — | EP | disclosed |
| EP-0529100-A1 | INDOLINOSPIROBENZOPYRAN DERIVATIVE | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1993-03-03 | — | — | EP | disclosed |