SCHEMBL6093583

SCHEMBL6093583

C=C1N(CCCC)c2ccccc2C1(C)C

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.53
CYP1A2 P05177 1/20 0.53
CYP2D6 P10635 1/20 0.53
ALDH1A1 P00352 7/20 0.44
MEN1 O00255 5/20 0.44
MAPT P10636 3/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
GPR55 Q9Y2T6 2/20 0.44
GLA P06280 1/20 0.44
HTT P42858 1/20 0.44
KDM4E B2RXH2 2/20 0.42
GAA P10253 1/20 0.42
HPGD P15428 1/20 0.42
ALOX12 P18054 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
SCN9A Q15858 3/20 0.40
TP53 P04637 1/20 0.39
ALDH2 P05091 1/20 0.39
ALDH3A1 P30838 1/20 0.39
RAB9A P51151 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10448669 0.95 KMT2A (0.51) KMT2ACYP1A2CYP2D6ALDH1A1MEN1
SCHEMBL9736812 0.94 KMT2A (0.50) KMT2ACYP1A2CYP2D6ALDH1A1MEN1
SCHEMBL14134758 0.94 KMT2A (0.50) KMT2ACYP1A2CYP2D6ALDH1A1MEN1
SCHEMBL8555578 0.94 KMT2A (0.50) KMT2ACYP1A2CYP2D6ALDH1A1MEN1
SCHEMBL19746373 0.94 KMT2A (0.50) KMT2ACYP1A2CYP2D6ALDH1A1MEN1
SCHEMBL8475420 0.94 KMT2A (0.50) KMT2ACYP1A2CYP2D6ALDH1A1MEN1
SCHEMBL9868831 0.94 KMT2A (0.50) KMT2ACYP1A2CYP2D6ALDH1A1MEN1
SCHEMBL8708894 0.94 KMT2A (0.50) KMT2ACYP1A2CYP2D6ALDH1A1MEN1
SCHEMBL5573253 0.90 KMT2A (0.47) KMT2ACYP1A2CYP2D6ALDH1A1MEN1
SCHEMBL30996203 0.90 CYP1A2 (0.55) KMT2ACYP1A2CYP2D6MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7943203-B2 Colored curable composition, colored pattern and color filter using the same FUJIFILM CORPORATION (JP) 2011-05-17 US disclosed
US-7862163-B2 Image forming method and image forming apparatus FUJIFILM CORPORATION (JP) 2011-01-04 US disclosed
US-7635181-B2 Ink for ink jet-recording curable through irradiation with a radioactive ray and method for preparing lithographic printing plates using the same FUJIFILM CORPORATION (JP) 2009-12-22 US disclosed
US-20090085017-A1 COLORED CURABLE COMPOSITION, COLORED PATTERN AND COLOR FILTER USING THE SAME FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed
US-20080012887-A1 Image forming method and image forming apparatus FUJIFILM CORPORATION 2008-01-17 US disclosed
US-7132550-B2 Process for the preparation of cyanine dyes with polysulfonate anions EASTMAN KODAK COMPANY (US) 2006-11-07 US disclosed
EP-1535968-A2 Process for the preparation of cyanine dyes with polysulfonate anions Kodak Polychrome Graphics, LLC (US) 2005-06-01 EP disclosed
US-20050113546-A1 Process for the preparation of cyanine dyes with polysulfonate anions KODAK REALTY INC. 2005-05-26 US disclosed
EP-1152001-B1 SQUARYLIUM COMPOUND AND OPTICAL RECORDING MEDIUM CONTAINING THE SAME KYOWA HAKKO KOGYO KK (JP) 2003-09-03 EP disclosed
US-6596364-B2 Assymetric squarylium dyes for use in digital versatile disc-recording medium KYOWA HAKKO KOGYO CO., LTD. (JP) 2003-07-22 US disclosed
US-20030082330-A1 Squarylium compounds and optical recording medium containing the same KYOWA HAKKO CHEMICAL CO., LTD. (FORMERLY KYOWA YUKA CO., LTD.) (JP) 2003-05-01 US disclosed
EP-1152001-A9 SQUARYLIUM COMPOUND AND OPTICAL RECORDING MEDIUM CONTAINING THE SAME KYOWA HAKKO KOGYO CO., LTD. (JP) 2002-02-27 EP disclosed
EP-1152001-A1 SQUARYLIUM COMPOUND AND OPTICAL RECORDING MEDIUM CONTAINING THE SAME KYOWA HAKKO KOGYO CO., LTD. (JP) 2001-11-07 EP disclosed
US-5149819-A Squarylium compounds and optical information recording medium using the same RICOH COMPANY, LTD. (JP) 1992-09-22 US disclosed
US-5085909-A SQUARYLIUM COMPOUNDS AND OPTICAL INFORMATION RECORDING MEDIUM USING THE SAME RICOH COMPANY, LTD. (JP) 1992-02-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050113546-A1 Process for the preparation of cyanine dyes with polysulfonate anions MPST, ALG3, KIT KMT2A 1555/4885CYP1A2 3018/4885CYP2D6 2949/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.