Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 5/20 | 0.42 |
| ▸ | CHEK2 | O96017 | 3/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8551675 | 0.86 | CHEK2 (0.44) | CHEK2 | |
| SCHEMBL8556872 | 0.83 | NPY1R (0.44) | NPY1RDHODHITGB3ITGA2BNPC1 | |
| SCHEMBL8556235 | 0.82 | NPY1R (0.48) | NPY1RDHODHNPC1RAB9APOLB | |
| SCHEMBL8554458 | 0.79 | NPY1R (0.47) | NPY1RDHODHITGB3ITGA2BNPC1 | |
| SCHEMBL8554215 | 0.79 | NPY1R (0.49) | NPY1RDHODHNPC1RAB9APOLB | |
| Trifluoroacetic Acid SCHEMBL8552526 | 0.78 | NPY1R (0.41) | NPY1RDHODHITGB3ITGA2BNPC1 | |
| SCHEMBL8553363 | 0.77 | NPY1R (0.48) | NPY1R | |
| SCHEMBL8553502 | 0.77 | NPY1R (0.48) | NPY1RDHODHITGB3ITGA2BNPC1 | |
| Trifluoroacetic Acid SCHEMBL8555689 | 0.76 | NPY1R (0.45) | NPY1RDHODH | |
| SCHEMBL8550284 | 0.76 | NPY1R (0.47) | NPY1RDHODHITGB3ITGA2BNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871442-A1 | BENZIMIDZOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1998-10-21 | — | — | EP | disclosed |
| WO-1997025041-A1 | BENZIMIDZOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1997-07-17 | — | — | WO | disclosed |