Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 3/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.41 |
| ▸ | YAP1 | P46937 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555610 | 0.86 | NPY1R (0.42) | CHEK2 | |
| SCHEMBL8557780 | 0.84 | GPR119 (0.44) | CHEK2GPR119PRMT5FAAH | |
| SCHEMBL8555211 | 0.84 | GPR119 (0.45) | CHEK2GPR119PRMT5FAAH | |
| SCHEMBL8551336 | 0.82 | GPR119 (0.47) | CHEK2GPR119PRMT5FAAH | |
| SCHEMBL8552756 | 0.82 | GPR119 (0.45) | CHEK2GPR119PRMT5FAAH | |
| SCHEMBL8552821 | 0.81 | GPR119 (0.42) | CHEK2GPR119PRMT5FAAH | |
| SCHEMBL8553734 | 0.81 | GPR119 (0.42) | CHEK2GPR119PRMT5FAAH | |
| SCHEMBL8553086 | 0.81 | GPR119 (0.44) | CHEK2GPR119PRMT5FAAH | |
| SCHEMBL8556312 | 0.80 | PRMT5 (0.51) | GPR119PRMT5YAP1 | |
| SCHEMBL8554479 | 0.78 | NPY1R (0.45) | PRMT5MAPTFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871442-A1 | BENZIMIDZOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1998-10-21 | — | — | EP | disclosed |
| WO-1997025041-A1 | BENZIMIDZOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1997-07-17 | — | — | WO | disclosed |