Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 2/20 | 0.43 |
| ▸ | GRK5 | P34947 | 2/20 | 0.43 |
| ▸ | CDK8 | P49336 | 2/20 | 0.43 |
| ▸ | PRKX | P51817 | 2/20 | 0.43 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.43 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.43 |
| ▸ | CAMK2A | Q9UQM7 | 2/20 | 0.43 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | FLT1 | P17948 | 1/20 | 0.43 |
| ▸ | LTK | P29376 | 1/20 | 0.43 |
| ▸ | NEK2 | P51955 | 1/20 | 0.43 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.43 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8552945 | 0.88 | CHEK1 (0.44) | METGRK5CDK8PRKXTYRO3 | |
| SCHEMBL8555388 | 0.88 | ADORA3 (0.57) | METGRK5CDK8PRKXTYRO3 | |
| SCHEMBL8557555 | 0.87 | PDE5A (0.45) | METGRK5CDK8PRKXTYRO3 | |
| SCHEMBL8559781 | 0.86 | CHEK1 (0.42) | METGRK5CDK8PRKXTYRO3 | |
| SCHEMBL8555096 | 0.85 | ADORA3 (0.53) | METGRK5CDK8PRKXTYRO3 | |
| SCHEMBL8553369 | 0.85 | PDE5A (0.45) | METGRK5CDK8PRKXTYRO3 | |
| SCHEMBL8557227 | 0.85 | ADORA3 (0.54) | METGRK5CDK8PRKXTYRO3 | |
| SCHEMBL8554275 | 0.85 | CHEK1 (0.48) | METGRK5CDK8PRKXTYRO3 | |
| SCHEMBL8558058 | 0.84 | CHEK1 (0.41) | METGRK5CDK8PRKXTYRO3 | |
| SCHEMBL8557524 | 0.84 | CHEK1 (0.51) | METGRK5CDK8PRKXTYRO3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691970-B1 | IMIDAZOLOQUINOXALINONE DERIVATIVES AS EAA ANTAGONISTS | BASF AG (DE) | 1998-11-11 | — | — | EP | disclosed |