Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 4/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 5/20 | 0.42 |
| ▸ | THRA | P10827 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30832950 | 0.99 | METAP1 (0.47) | METAP1SIRT2THRATHRBACHE | |
| SCHEMBL17675468 | 0.82 | METAP1 (0.45) | METAP1ACHE | |
| SCHEMBL7882430 | 0.82 | METAP1 (0.52) | METAP1ACHEADRA2APNMTADRA2B | |
| SCHEMBL8809427 | 0.80 | TP53 (0.43) | THRATHRB | |
| SCHEMBL8808330 | 0.80 | GRM2 (0.43) | METAP1THRATHRBACHECYP19A1 | |
| SCHEMBL8030964 | 0.80 | MEN1 (0.44) | METAP1THRATHRBACHECYP19A1 | |
| SCHEMBL8556555 | 0.80 | ACHE (0.60) | METAP1THRATHRBACHECYP19A1 | |
| SCHEMBL17675551 | 0.79 | METAP1 (0.47) | METAP1ACHE | |
| SCHEMBL6528990 | 0.78 | ACHE (0.62) | METAP1ACHECYP19A1 | |
| SCHEMBL27347569 | 0.77 | ACHE (0.56) | METAP1THRATHRBACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0546338-B1 | Mesomorphic compound, liquid crystal composition, liquid crystal device, display apparatus and display method | CANON KK (JP) | 1998-02-04 | — | — | EP | disclosed |
| EP-0555843-B1 | Mesomorphic compound, liquid crystal composition, liquid crystal device, display apparatus and display method | CANON KK (JP) | 1997-05-14 | — | — | EP | disclosed |
| US-5385692-A | Improved response | CANON KABUSHIKI KAISHA (JP) | 1995-01-31 | — | — | US | disclosed |
| US-5354501-A | Improved response and helical pitch | CANON KABUSHIKI KAISHA (JP) | 1994-10-11 | — | — | US | disclosed |
| EP-0555843-A1 | Mesomorphic compound, liquid crystal composition, liquid crystal device, display apparatus and display method | CANON KABUSHIKI KAISHA (JP) | 1993-08-18 | — | — | EP | disclosed |
| EP-0546338-A1 | Mesomorphic compound, liquid crystal composition, liquid crystal device, display apparatus and display method | CANON KABUSHIKI KAISHA (JP) | 1993-06-16 | — | — | EP | disclosed |