Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERBB2 | P04626 | 6/20 | 0.87 |
| ▸ | EGFR | P00533 | 8/20 | 0.60 |
| ▸ | RET | P07949 | 4/20 | 0.60 |
| ▸ | KDR | P35968 | 3/20 | 0.60 |
| ▸ | LCK | P06239 | 2/20 | 0.59 |
| ▸ | CLK1 | P49759 | 1/20 | 0.57 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.57 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.57 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8894692 | 0.99 | ERBB2 (0.86) | ERBB2EGFRRETKDRLCK | |
| SCHEMBL8555757 | 0.93 | ERBB2 (1.00) | ERBB2EGFRRETKDRLCK | |
| Hydrochloric Acid SCHEMBL8894722 | 0.92 | ERBB2 (0.98) | ERBB2EGFRRETKDRLCK | |
| SCHEMBL8558469 | 0.84 | ERBB2 (0.85) | ERBB2EGFRKDRABCG2 | |
| SCHEMBL8556333 | 0.84 | EGFR (0.65) | ERBB2EGFRRETKDRLCK | |
| Hydrochloric Acid SCHEMBL8893639 | 0.83 | ERBB2 (0.84) | ERBB2EGFRKDRABCG2 | |
| SCHEMBL8558954 | 0.83 | ERBB2 (0.63) | ERBB2EGFRRETKDRLCK | |
| Hydrochloric Acid SCHEMBL8896116 | 0.83 | EGFR (0.64) | ERBB2EGFRRETKDRLCK | |
| SCHEMBL18158179 | 0.83 | EGFR (0.79) | ERBB2EGFRRETKDRLCK | |
| Hydrochloric Acid SCHEMBL8810155 | 0.82 | EGFR (0.79) | ERBB2EGFRRETKDRLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0843671-A1 | HETEROCYCLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLAXO GROUP LIMITED (GB) | 1998-05-27 | — | — | EP | claimed |
| WO-1997003069-A1 | HETEROCYCLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLAXO GROUP LIMITED (GB) | 1997-01-30 | — | — | WO | claimed |
| EP-1364212-B1 | THREE HYBRID ASSAY SYSTEM | GPC BIOTECH AG (DE) | 2011-02-02 | — | — | EP | disclosed |
| EP-1975620-A2 | Three hybrid assay system | GPC Biotech AG (DE) | 2008-10-01 | — | — | EP | disclosed |
| EP-0843671-A1 | HETEROCYCLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLAXO GROUP LIMITED (GB) | 1998-05-27 | — | — | EP | disclosed |
| WO-1997003069-A1 | HETEROCYCLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLAXO GROUP LIMITED (GB) | 1997-01-30 | — | — | WO | disclosed |