SCHEMBL8555789

SCHEMBL8555789

CCCCC1CCCCN1N

nearest known ligand 0.45

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 3/20 0.45
CHRNA7 P36544 3/20 0.45
CHRNA4 P43681 3/20 0.45
CYP1A2 P05177 2/20 0.43
S1PR1 P21453 3/20 0.41
S1PR3 Q99500 3/20 0.41
S1PR5 Q9H228 3/20 0.41
DPP4 P27487 1/20 0.39
NOS1 P29475 2/20 0.36
NOS2 P35228 2/20 0.36
S1PR4 O95977 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5810243 0.94 CHRNB2 (0.51) CHRNB2CHRNA7CHRNA4CYP1A2S1PR1
SCHEMBL28173258 0.94 CYP1A2 (0.40) CHRNB2CHRNA7CHRNA4CYP1A2S1PR1
SCHEMBL8557135 0.92 CHRNB2 (0.54) CHRNB2CHRNA7CHRNA4CYP1A2S1PR1
SCHEMBL5140421 0.88 S1PR1 (0.45) CHRNB2CHRNA7CHRNA4CYP1A2S1PR1
SCHEMBL6215101 0.88 PSEN1 (0.40) CHRNB2CHRNA7CHRNA4CYP1A2S1PR1
SCHEMBL6395663 0.86 S1PR1 (0.48) CHRNB2CHRNA7CHRNA4S1PR1S1PR3
SCHEMBL17121688 0.79
SCHEMBL8555817 0.79
SCHEMBL17121689 0.79
SCHEMBL15508580 0.78 CYP1A2 (0.60) CHRNB2CHRNA7CHRNA4CYP1A2S1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114853733-B Method for preparing light stabilizer 2020 by using skeleton method 宿迁联盛科技股份有限公司 2023-09-01 CN claimed
CN-114853733-A Method for preparing light stabilizer 2020 by skeleton method 宿迁联盛科技股份有限公司 2022-08-05 CN claimed
CN-114853733-B Method for preparing light stabilizer 2020 by using skeleton method 宿迁联盛科技股份有限公司 2023-09-01 CN disclosed
CN-114853733-B Method for preparing light stabilizer 2020 by using skeleton method 宿迁联盛科技股份有限公司 2023-09-01 CN disclosed
CN-114853733-A Method for preparing light stabilizer 2020 by skeleton method 宿迁联盛科技股份有限公司 2022-08-05 CN disclosed
CN-114853733-A Method for preparing light stabilizer 2020 by skeleton method 宿迁联盛科技股份有限公司 2022-08-05 CN disclosed
US-5811576-A 1-CARBOXY-2-LOWERALKYL-3,4,6-TRI(HALO)BENZENES; GRAMPOSITIVE AND-NEGATIVE BACTERIA; INFECTIONS; STERILIZATION OF MEDICAL EQUIPMENT OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) 1998-09-22 US disclosed
US-5723648-A Intermediates for anti-microbial benzoheterocyclic compounds OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) 1998-03-03 US disclosed
EP-0823413-A2 Benzoheterocyclic compounds OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1998-02-11 EP disclosed
US-5591744-A 1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXYLATE DERIVATIVES; MICROBIOCIDES OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) 1997-01-07 US disclosed
US-5563138-A 4-OXOQUINOLINE-3-CARBOXYLIC ACID COMPOUNDS HAVING ANTIMICROBIAL ACTIVITY OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) 1996-10-08 US disclosed
US-5495020-A CHEMICAL INTERMEDIATE FOR BACTERICIDES, MICROBIOCIDES, DISINFECTANTS; SIDE EFFECT REDUCTION, ABSORPTION OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) 1996-02-27 US disclosed
US-5290934-A Benzoheterocyclic compounds OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) 1994-03-01 US disclosed
EP-0565132-A2 Benzoheterocyclic compounds OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1993-10-13 EP disclosed
US-3965220-A AMINE CATALYST MONSANTO COMPANY (US) 1976-06-22 US disclosed