⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556093 | 1.00 | — | — | |
| SCHEMBL535753 | 0.83 | KDM4E (0.37) | — | |
| SCHEMBL31635602 | 0.83 | — | — | |
| SCHEMBL21372316 | 0.81 | — | — | |
| SCHEMBL28538957 | 0.79 | — | — | |
| SCHEMBL26159885 | 0.79 | — | — | |
| SCHEMBL21373970 | 0.78 | — | — | |
| SCHEMBL534980 | 0.76 | HSD17B10 (0.43) | — | |
| SCHEMBL535005 | 0.73 | LMNA (0.46) | — | |
| SCHEMBL1300378 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3778553-A1 | METHOD FOR PREPARING HEXAHYDROFURO-FURANOL DERIVATIVE, INTERMEDIATE THEREOF AND PREPARATION METHOD THEREFOR | Jiangsu Ruike Medical Science And Technology Co., Ltd. (CN) | 2021-02-17 | — | — | EP | disclosed |
| WO-2019196263-A1 | METHOD FOR PREPARING HEXAHYDROFURO-FURANOL DERIVATIVE, INTERMEDIATE THEREOF AND PREPARATION METHOD THEREFOR | 江苏瑞科医药科技有限公司 | 2019-10-17 | — | — | WO | disclosed |
| WO-2019174176-A1 | PREPARATION METHOD FOR HEXAHYDROFURO-FURAN-OL DERIVATIVE AND INTERMEDIATE OF DERIVATIVE AND PREPARATION METHOD THEREFOR | 江苏瑞科医药科技有限公司 | 2019-09-19 | — | — | WO | disclosed |
| EP-0395219-B1 | Cephalosporins and their homologues, process for their preparation and pharmaceutical compositions | PFIZER (US) | 1998-09-30 | — | — | EP | disclosed |
| US-5246926-A | Bactericides | BEECHAM GROUP P.L.C. (GB) | 1993-09-21 | — | — | US | disclosed |
| EP-0395219-A2 | Cephalosporins and their homologues, process for their preparation and pharmaceutical compositions | Beecham Group p.l.c. (GB) | 1990-10-31 | — | — | EP | disclosed |