Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CTSC | P53634 | 1/20 | 0.43 |
| ▸ | ANPEP | P15144 | 2/20 | 0.42 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.42 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | CTSG | P08311 | 1/20 | 0.41 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.41 |
| ▸ | CMA1 | P23946 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15989057 | 0.89 | SMN1; SMN2 (0.46) | SMN1; SMN2HPGDMEN1HTTKMT2A | |
| SCHEMBL27878100 | 0.87 | SMN1; SMN2 (0.47) | SMN1; SMN2HPGDMEN1HTTKMT2A | |
| SCHEMBL27878101 | 0.87 | SMN1; SMN2 (0.47) | SMN1; SMN2HPGDMEN1HTTKMT2A | |
| SCHEMBL2307679 | 0.87 | LTA4H (0.55) | SMN1; SMN2HPGDMEN1HTTKMT2A | |
| SCHEMBL2307682 | 0.87 | LTA4H (0.55) | SMN1; SMN2HPGDMEN1HTTKMT2A | |
| SCHEMBL27878054 | 0.87 | LTA4H (0.55) | SMN1; SMN2HPGDMEN1HTTKMT2A | |
| Hydrochloric Acid SCHEMBL29264506 | 0.85 | LTA4H (0.54) | SMN1; SMN2HPGDMEN1HTTKMT2A | |
| SCHEMBL12967040 | 0.85 | SLC7A5 (0.53) | LTA4HANPEP | |
| SCHEMBL2635410 | 0.80 | SMN1; SMN2 (0.55) | SMN1; SMN2GRIK1CTSCANPEPERAP1 | |
| SCHEMBL3712742 | 0.80 | SMN1; SMN2 (0.55) | SMN1; SMN2GRIK1CTSCANPEPERAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915829-A1 | DIAGNOSTIC IMAGING CONTRAST AGENT WITH IMPROVED IN-SERUM-RELAXIVITY | BRACCO S.p.A. (IT) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998005625-A1 | DIAGNOSTIC IMAGING CONTRAST AGENT WITH IMPROVED IN-SERUM-RELAXIVITY | BRACCO S.P.A. (IT) | 1998-02-12 | — | — | WO | disclosed |