Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555612 | 0.89 | PTPN1 (0.43) | PTPN1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL13141213 | 0.84 | PTPN1 (0.42) | PTPN1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL2442541 | 0.80 | PPARA (0.53) | PTPN1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL12147577 | 0.80 | PTPN1 (0.44) | PTPN1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL23348672 | 0.78 | PTPN1 (0.44) | PTPN1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL30188377 | 0.78 | PTPN1 (0.44) | PTPN1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL8555264 | 0.78 | HPGD (0.37) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL8593499 | 0.77 | PTPN1 (0.43) | PTPN1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL20593092 | 0.77 | P4HTM (0.52) | PTPN1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL25659622 | 0.76 | PTPN1 (0.41) | PTPN1PSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641770-B1 | NOVEL COMPOUND WITH PLATELET AGGREGATION INHIBITOR ACTIVITY | MEIJI SEIKA CO (JP) | 1998-05-13 | — | — | EP | disclosed |
| US-5698692-A | INHIBIT BINDING BETWEEN PLATELET MEMBRANE GLYCOPROTEIN AND FIBRINOGEN | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1997-12-16 | — | — | US | disclosed |
| US-5594004-A | CARDIOVASCULAR DISORDERS AND ANTICOAGULANTS | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1997-01-14 | — | — | US | disclosed |
| EP-0641770-A1 | NOVEL COMPOUND WITH PLATELET AGGREGATION INHIBITOR ACTIVITY | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1995-03-08 | — | — | EP | disclosed |