SCHEMBL8555264

SCHEMBL8555264

CC(C)(C)OC(=O)COc1cnc(CCO)cc1OCC(=O)OC(C)(C)C

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.37
KDM4E B2RXH2 3/20 0.37
ALDH1A1 P00352 3/20 0.37
HSD17B10 Q99714 2/20 0.37
POLB P06746 2/20 0.37
MEN1 O00255 1/20 0.37
TSHR P16473 1/20 0.37
KMT2A Q03164 1/20 0.37
MAPT P10636 2/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
DDB1 Q16531 1/20 0.34
CRBN Q96SW2 1/20 0.34
TNFRSF1A P19438 1/20 0.34
PSEN1 P49768 2/20 0.33
PSEN2 P49810 2/20 0.33
APH1B Q8WW43 2/20 0.33
NCSTN Q92542 2/20 0.33
APH1A Q96BI3 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8556784 0.89 HPGD (0.38) HPGDKDM4EALDH1A1HSD17B10POLB
SCHEMBL8554570 0.78 MAPT (0.40) HPGDKDM4EALDH1A1POLBMAPT
SCHEMBL8555196 0.78 HPGD (0.37) HPGDKDM4EALDH1A1HSD17B10POLB
SCHEMBL8556076 0.78 PTPN1 (0.41) HPGDKDM4EALDH1A1HSD17B10POLB
SCHEMBL8558830 0.77 ALDH1A1 (0.40) HPGDKDM4EALDH1A1HSD17B10POLB
SCHEMBL8555443 0.76 ALDH1A1 (0.37) HPGDKDM4EALDH1A1HSD17B10POLB
SCHEMBL8555263 0.75 HPGD (0.39) HPGDKDM4EALDH1A1HSD17B10POLB
SCHEMBL22535966 0.74 HPGD (0.47) HPGDKDM4EALDH1A1HSD17B10POLB
SCHEMBL8552801 0.74 HPGD (0.41) HPGDKDM4EALDH1A1HSD17B10POLB
Hydrochloric Acid SCHEMBL8553588 0.73 HPGD (0.40) HPGDKDM4EALDH1A1HSD17B10POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0641770-B1 NOVEL COMPOUND WITH PLATELET AGGREGATION INHIBITOR ACTIVITY MEIJI SEIKA CO (JP) 1998-05-13 EP disclosed
US-5698692-A INHIBIT BINDING BETWEEN PLATELET MEMBRANE GLYCOPROTEIN AND FIBRINOGEN MEIJI SEIKA KABUSHIKI KAISHA (JP) 1997-12-16 US disclosed
US-5594004-A CARDIOVASCULAR DISORDERS AND ANTICOAGULANTS MEIJI SEIKA KABUSHIKI KAISHA (JP) 1997-01-14 US disclosed
EP-0641770-A1 NOVEL COMPOUND WITH PLATELET AGGREGATION INHIBITOR ACTIVITY MEIJI SEIKA KABUSHIKI KAISHA (JP) 1995-03-08 EP disclosed