Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
| ▸ | CASP7 | P55210 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.47 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | RXRB | P28702 | 3/20 | 0.41 |
| ▸ | RXRA | P19793 | 2/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | GUSB | P08236 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30942586 | 1.00 | MAPT (0.60) | MAPTSMN1; SMN2TDP1TP53CYP3A4 | |
| SCHEMBL6311040 | 0.80 | MAPT (0.58) | MAPTSMN1; SMN2CYP3A4MAPK1TNFRSF1A | |
| SCHEMBL9319237 | 0.80 | MAPT (0.58) | MAPTSMN1; SMN2CYP3A4MAPK1TNFRSF1A | |
| SCHEMBL26877087 | 0.80 | MAPT (0.68) | MAPTSMN1; SMN2CYP3A4BCHELMNA | |
| SCHEMBL8554890 | 0.78 | BCHE (0.43) | MAPTSMN1; SMN2BCHELMNANPC1 | |
| SCHEMBL2307743 | 0.75 | MAPT (1.00) | MAPTSMN1; SMN2TDP1TP53CYP3A4 | |
| SCHEMBL2307737 | 0.75 | MAPT (1.00) | MAPTSMN1; SMN2TDP1TP53CYP3A4 | |
| SCHEMBL7616179 | 0.75 | BCHE (0.58) | MAPTSMN1; SMN2TDP1ALOX15BCHE | |
| SCHEMBL7583119 | 0.74 | CA1 (0.46) | MAPTMAPK1HSD17B10BCHELMNA | |
| SCHEMBL10621808 | 0.73 | GRIK1 (0.51) | TDP1RXRBRXRACYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5767146-A | Anti-osteopathic composition | HOECHST JAPAN LIMITED (JP) | 1998-06-16 | — | — | US | disclosed |
| US-5716995-A | TREATING OR PREVENTING BONE DISEASES BY ADMINISTERING PHENOLIC, HETERO- OR NAPHTHYL- DERIVATIVES OF 1-HYDROXY-3-OXO-1-PROPENYL BENZOIC ACID TO PROMOTE OSTEOGENESIS | HOECHST JAPAN LIMITED (JP) | 1998-02-10 | — | — | US | disclosed |
| US-5703128-A | TREATING OSTEOPOROSIS, BONE FRACTURES | HOECHST JAPAN LIMITED (JP) | 1997-12-30 | — | — | US | disclosed |