Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | GUSB | P08236 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.39 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.39 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.39 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.39 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.39 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6311040 | 0.80 | MAPT (0.58) | BCHELMNAMAPTRAB9ANPC1 | |
| SCHEMBL9319237 | 0.80 | MAPT (0.58) | BCHELMNAMAPTRAB9ANPC1 | |
| SCHEMBL30942586 | 0.78 | MAPT (0.60) | BCHELMNAMAPTRAB9ANPC1 | |
| SCHEMBL8556077 | 0.78 | MAPT (0.60) | BCHELMNAMAPTRAB9ANPC1 | |
| SCHEMBL8972681 | 0.75 | MAPK1 (0.61) | MAPTRAB9ANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL8972673 | 0.75 | MAPK1 (0.61) | MAPTRAB9ANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL7616179 | 0.75 | BCHE (0.58) | BCHELMNAMAPTGUSBKDM4E | |
| SCHEMBL7583119 | 0.74 | CA1 (0.46) | BCHELMNAMAPTRAB9ANPC1 | |
| SCHEMBL10496539 | 0.73 | GRIK1 (0.51) | LMNAMAPTTYRKDM4EALDH1A1 | |
| SCHEMBL9797948 | 0.73 | GRIK1 (0.51) | LMNAMAPTTYRKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5767146-A | Anti-osteopathic composition | HOECHST JAPAN LIMITED (JP) | 1998-06-16 | — | — | US | disclosed |
| US-5716995-A | TREATING OR PREVENTING BONE DISEASES BY ADMINISTERING PHENOLIC, HETERO- OR NAPHTHYL- DERIVATIVES OF 1-HYDROXY-3-OXO-1-PROPENYL BENZOIC ACID TO PROMOTE OSTEOGENESIS | HOECHST JAPAN LIMITED (JP) | 1998-02-10 | — | — | US | disclosed |
| US-5703128-A | TREATING OSTEOPOROSIS, BONE FRACTURES | HOECHST JAPAN LIMITED (JP) | 1997-12-30 | — | — | US | disclosed |