Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.55 |
| ▸ | NPC1 | O15118 | 8/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556385 | 0.88 | RAB9A (0.55) | RAB9ANPC1SMN1; SMN2POLBTDP1 | |
| SCHEMBL8553989 | 0.84 | RAB9A (0.47) | RAB9ANPC1SMN1; SMN2POLBTDP1 | |
| SCHEMBL8551977 | 0.81 | RAB9A (0.49) | RAB9ANPC1SMN1; SMN2POLBTDP1 | |
| SCHEMBL8554128 | 0.81 | RAB9A (0.46) | RAB9ANPC1SMN1; SMN2POLBTDP1 | |
| SCHEMBL7687482 | 0.80 | RAB9A (0.63) | RAB9ANPC1SMN1; SMN2POLBTDP1 | |
| SCHEMBL7690279 | 0.80 | RAB9A (0.56) | RAB9ANPC1SMN1; SMN2POLBTDP1 | |
| SCHEMBL7689804 | 0.78 | RAB9A (0.63) | RAB9ANPC1SMN1; SMN2POLBTDP1 | |
| SCHEMBL8555586 | 0.77 | RAB9A (0.47) | RAB9ANPC1SMN1; SMN2POLBTDP1 | |
| SCHEMBL8556128 | 0.76 | RAB9A (0.46) | RAB9ANPC1SMN1; SMN2POLBTDP1 | |
| SCHEMBL7691214 | 0.75 | RAB9A (0.59) | RAB9ANPC1SMN1; SMN2POLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871442-A1 | BENZIMIDZOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1998-10-21 | — | — | EP | disclosed |
| WO-1997025041-A1 | BENZIMIDZOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1997-07-17 | — | — | WO | disclosed |