Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.32 |
| ▸ | CDK4 | P11802 | 2/20 | 0.32 |
| ▸ | CCND1 | P24385 | 2/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.32 |
| ▸ | CDK2 | P24941 | 2/20 | 0.32 |
| ▸ | CAMK2B | Q13554 | 2/20 | 0.32 |
| ▸ | CAMK2G | Q13555 | 2/20 | 0.32 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.32 |
| ▸ | CAMK2A | Q9UQM7 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | GSK3A | P49840 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.30 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8559795 | 0.95 | KDM4E (0.32) | KDM4EALDH1A1HPGDHSD17B10MAPK10 | |
| SCHEMBL8556098 | 0.74 | SLC6A2 (0.37) | KDM4EALDH1A1HPGDHSD17B10MAPK10 | |
| SCHEMBL8557618 | 0.74 | — | — | |
| SCHEMBL11206986 | 0.73 | GSK3B (0.45) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL10712855 | 0.73 | GSK3B (0.45) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL11015946 | 0.73 | GSK3B (0.45) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL10914947 | 0.73 | GSK3B (0.45) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL27815646 | 0.73 | KDM4E (0.39) | KDM4EALDH1A1HPGDHSD17B10MAPK10 | |
| SCHEMBL6598413 | 0.72 | KDM4E (0.43) | KDM4EALDH1A1HPGDHSD17B10CCNE2 | |
| SCHEMBL5970012 | 0.72 | GSK3B (0.50) | KDM4EALDH1A1HPGDHSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0575954-B1 | Aminoalkylcarbamic esters of eseroline suitable for use as cholinesterase acitivity inhibitors and relative preparation process | MEDIOLANUM FARMACEUTICI SRL (IT) | 1998-09-02 | — | — | EP | disclosed |
| US-5424451-A | Used as cholinesterase activity inhibitors | MEDIOLANUM FARMACEUTICI S.P.A. (IT) | 1995-06-13 | — | — | US | disclosed |
| US-5302593-A | Aminoalkylcarbamic esters of eseroline suitable for use as chlorinesterase activity inhibitors | MEDIOLANUM FARMACEUTICI S.P.A. (IT) | 1994-04-12 | — | — | US | disclosed |
| EP-0575954-A1 | Aminoalkylcarbamic esters of eseroline suitable for use as cholinesterase acitivity inhibitors and relative preparation process | MEDIOLANUM FARMACEUTICI S.P.A. (IT) | 1993-12-29 | — | — | EP | disclosed |